ncRNA name | hsa-miR-34a |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | transfection, qRT-PCR, Western blot, luciferase assay, ELISA, MTT assay, flow cytometry |
Expression pattern | up-regulated |
Functional description | MEG3 could alleviate HG-inducing apoptosis and inflammation via inhibiting NF-κB signaling pathway by targeting miR-34a/SIRT1 axis. |
PubMed ID | 30529346 |
Year | 2019 |
Title | LncRNA-MEG3 alleviates high glucose induced inflammation and apoptosis of retina epithelial cells via regulating miR-34a/SIRT1 axis. |
Drug-related ncRNA | NO |
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